DEXMEDETOMIDINE: AS NOVEL PREMEDICATION

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Low-Dose Intramuscular Dexmedetomidine as Premedication: A Randomized Controlled Trial

BACKGROUND Dexmedetomidine-induced bradycardia or hypotension has recently attracted considerable attention because of potentially grave consequences, including sinus arrest and refractory cardiogenic shock. A route other than intravenous injection or a low dose may help minimize cardiovascular risks associated with dexmedetomidine. However, few studies have addressed the clinical effects of lo...

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Comparison Hemodynamic Effects of Midazolam and Dexmedetomidine as a Premedication in Patients Undergoing Upper Limb Surgeries: A Double-blind Intervention

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Dexmedetomidine versus Midazolam as Premedication in Anesthesia: A Meta-Analysis from Randomized Controlled Clinical Trials

Dexmedetomidine [Dex] is an α2-adrenoceptor agonist which provides sedation, analgesia and anxiolytic effects, thus making it a potentially useful anesthetic premedication. A number of clinical trials have been conducted to compare the sedative effect of Dex versus midazolam [Mdz], a conventional sedative agent in anesthesia. Nevertheless, consensus has not been achieved on which agent is super...

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Intranasal Dexmedetomidine as a Sedative Premedication for Patients Undergoing Suspension Laryngoscopy: A Randomized Double-Blind Study

BACKGROUND Intranasal dexmedetomidine, a well-tolerated and convenient treatment option, has been shown to induce a favorable perioperative anxiolysis in children. We investigate intranasal dexmedetomidine as a sedative premedication for anesthesia recovery in an adult population. METHODS A prospective randomized controlled trial; 81 adult patients scheduled for elective suspension laryngosco...

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Dexmedetomidine as a pediatric anesthetic premedication to reduce anxiety and to deter emergence delirium.

Presurgery anxiety in children may result in preoperative and postoperative complications. Emergence delirium (ED) is a mental disturbance common in children during recovery from general anesthesia. This study investigated the role of preoperative dexmedetomidine on parental separation anxiety and acceptance of wearing an anesthesia mask, and its effectiveness in reducing the incidence and seve...

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ژورنال

عنوان ژورنال: Journal of Evolution of Medical and Dental Sciences

سال: 2014

ISSN: 2278-4748,2278-4802

DOI: 10.14260/jemds/2014/3213